Fildena Extra Power

Fildena Extra Power is a potent anti-impotence medication used to treat men who suffer from sexual dysfunction, namely, impotence – a condition that consistently affects a person’s ability to achieve or maintain an erection, ability to achieve ejaculation or both.

This medicine is also helpful in treating pulmonary arterial hypertension – a disorder characterized by high blood pressure (hypertension) in the arteries of the lungs (pulmonary artery) for no apparent reason.

Fildena Extra Power is manufactured by Fortune Health Care and composed of an active ingredient Sildenafil, a representative of a PDE5 inhibitors drug family.

Indications

Treatment of erectile dysfunction.

Treatment of pulmonary arterial hypertension.

MOA (mechanism of action)

The physiologic mechanism of erection of the penis involves the release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Sildenafil has no direct relaxant effect on isolated human corpus cavernosum but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cGMP in the corpus cavernosum. When sexual stimulation causes a local release of NO, inhibition of PDE5 by Sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.

Sildenafil is an inhibitor of cGMP specific phosphodiesterase type-5 (PDE5) in the smooth muscle of the pulmonary vasculature, where PDE5 is responsible for the degradation of cGMP. Sildenafil, therefore, increases cGMP within pulmonary vascular smooth muscle cells resulting in relaxation. In patients with pulmonary hypertension, this can lead to vasodilation of the pulmonary vascular bed and, to a lesser degree, vasodilatation in the systemic circulation.

Dosage and administration

For patients with erectile dysfunction, Fildena Extra Power is taken orally, as needed, approximately 1 hour before sexual activity. However, it may be taken anywhere from 4 hours to 30 minutes before sexual activity. The maximum recommended dosing frequency is once per day. The accurate dose of this drug for treating pulmonary arterial hypertension should be recommended by a doctor and taken approximately 4-6 hours apart. Avoid consuming alcohol, grapefruit juice or fatty food while on Fildena® Extra Power tablets as it may change the way the medicine works.

Missed dose

If you miss a dose of Fildena Extra Power you should take it as soon as you remember. If it is the time for the next dose you should continue your regular dosing schedule. Do not take more than one dose of the medication when using it for the treatment of erectile dysfunction.

Overdose

In cases of overdose, standard supportive measures should be adopted as required.