Naprosyn

Naprosyn is an oral medication with anti-inflammatory, analgesic and antipyretic properties. Its active ingredient Naproxen belongs to the drug group called non-steroid anti-inflammatory drugs (NSAIDs) and it works by inhibiting cyclooxygenase isozymes and blocking the production of arachidonates. Naprosyn reduces pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gout. It can also be used in the management of acute musculoskeletal disorders like sprains, strains, low back pain, inflammation of tendon and muscle sheaths, and various soft tissue injuries.

Indications

treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, acute musculoskeletal disorders, and dysmenorrhea;

treatment of juvenile rheumatoid arthritis.

MOA (mechanism of action)

Naproxen is a non-steroidal anti-inflammatory analgesic compound with antipyretic properties. It blocks arachidonate binding which leads to the inhibition of both cyclooxygenase (COX) isozymes, COX-1 and COX-2. Their inhibition, especially of COX-2, ends up in the anti-inflammatory effect of the drug. The blockade of further production of arachidonate leads to analgesic and antipyretic properties of Naproxen.

Dosage

Use Naprosyn exactly as directed by your doctor. Do not take this medicine in larger amounts or for longer than recommended. Use the lowest dose that is effective in treating your condition.

Do not crush, chew, or break a Naprosyn tablet. Swallow it whole.You may take this medicine with or after food.

Please note that a sudden termination of Naprosyn treatment may cause adverse effects. Stop the treatment gradually, by lowering the dosage.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

Overdose

If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately. Symptoms of Naprosyn overdose include excessive fatigue, heartburn, lightheadedness, confusion, feeling drowsy, problems with breathing, problems with urination, vomiting, pain in the stomach, dyspepsia.

Storage

Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.